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The Cialis brand of tadalafil is used in men to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate).

Adcirca and Alyq are used in men and women to treat pulmonary arterial hypertension (PAH) and to improve exercise capacity.

Do not take Cialis for erectile dysfunction if you are taking Adcirca or Alyq for pulmonary arterial hypertension.

Tadalafil may also be used for purposes not listed in this medication guide.

Do not take tadalafil if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate, butyl nitrate or nitrite (“poppers”). Taking tadalafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

Some tadalafil can remain in your bloodstream for 2 or more days after each dose you take (longer if you have liver or kidney disease). Avoid nitrate use during this time.

Tell your doctor if you have ever had:

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  • high or low blood pressure;
  • liver disease;
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  • blood circulation problems;
  • a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
  • pulmonary veno-occlusive disease (PVOD);
  • a physical deformity of the penis (such as Peyronie’s disease), or an erection lasting longer than 4 hours;
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  • health problems that make sexual activity unsafe.

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Common side effects or health problems may include:

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  • Memory problems
  • Low blood pressure
  • Blurred vision
  • Abnormal ejaculation
  • Prolonged erections (priapism)

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